Alzheimers treatment, potential cure from alternative medicine. Alzheimer's news, information, therapy, study and research. Positive effects of galantamine and cocoa flavanols on Alzheimer's.
Niacinamide for Alzheimer's
As an Alzheimers treatment, large doses of niacinamide, also known as nicotinamide, a form of vitamin B3, "cured" Alzheimers disease in mice, reports health researcher/reporter Dr. David Williams. (Note: Niacinamide is NOT the same as niacin. Do not confuse the two.) "Rarely do you hear researchers using the word 'cured,' but that's exactly what happened," says Dr. Williams. "At the end of the Alzheimer's research study, the diseased mice that were treated with niacinamide performed just as well in memory tests as healthy mice. The niacinamide not only protected their brains from further memory loss, it also restored lost memory function."
(Note: Alzheimer's is frequently misspelled alzhiemers, alzhimers, alzeimers, altzheimers, alheimers, alsheimers, alzimers, alzhiemer's and alziemers.)
The professional writer/reporter who writes this site has no medical training. Always check with your doctor before trying anything you read here. Everyone is different, and what might be good for some people might be bad for you, considering your medical history and medications.
The study of this treatment for Alzheimer's disease, headed by Dr. Kim Green at the University of California at Irvine, involved four months of Alzheimers treatment with the human dose equivalent of 2000 to 3000 milligrams of niacinamide. "Cognitively, they were cured," said Dr. Green. "The vitamin completely prevented cognitive decline associated with the disease, bringing them back to the level they'd be at if they didn't have the pathology." Niacinamide also improved memory in mice without Alzheimer's.
The late Dr. William Kaufman did extensive research on niacinamide in the 1930s. Dr. Kaufman found that niacinamide moves in and out of the body quickly, so that smaller doses throughout the day are most effective, with 250 milligrams being the most the body could utilize at one time.
Dr. Kaufman and his wife took 250 milligrams of niacinamide every three waking hours (six doses) for at least 55 years, believing, as a result of his studies, that it helps prevent many of the physical and mental problems associated with aging, including arthritis, fatigue, muscle strength, loss of balance, depression, and cancer.
Niacinamide has been widely used for a variety of purposes for more than 60 years, and its safety is well known, says Jonathan Wright, M.D. In one of Dr. Kaufman's books, Kaufman described symptoms of niacinamide deficiency:
- Impaired memory, can't concentrate, easily distracted, slow thought, mental fog.
- Anxiety for no reason, resistant to making decisions and taking responsibility, lacks initiative, starts projects but never finishes, uncooperative.
- Quarrelsome, mean, intolerant, opinionated, unreasonable, unhappy, little things annoy, can't take a joke.
Dr. Kaufman found that these symptoms and more went away or improved a lot with the use of niacinamide, says Dr. Wright. Arthritis symptoms also improve or disappear with niacinamide, says Dr. Wright, but it's not a cure; the arthritis symptoms return if patients stop taking it.
Be certain what you're taking is NOT niacin, which can have many more side effects, particularly at high doses. Use niacinamide, not niacin, says Dr. Wright.
Based on Dr. Kaufman's work, Dr. Williams estimates that Alzheimer's patients "would achieve the best results if they took 250 mg every 1½ hours (a total of 12 doses)" for Alzheimers treatment. Dr. Wright recommends higher doses at less frequent intervals, which can cause side effects in a small number of people. For more info on Dr. Wrights regimen, read his newsletter.
Keep in mind that this Alzheimer's cure only works for mice so far. Given the outstanding results in mice, human trials for Alzheimers treatment are proceeding in Southern California and in England. In humans, taking 2000 to 3000 milligrams a day is "totally harmless," says Dr. Williams. The toxic dose would be nearly a pound of niacinamide daily, and there has never been a death reported from niacinamide supplementation.
Dr. Williams says, "I personally utilized Dr. Kaufman's protocols for several years and saw some amazing improvements; however, I saw even better responses after switching to a product without preservatives." One source of preservative-free niacinamide is Freeda Vitamins, 800-777-3737. www.freedavitamins.com.
"A 2008 University of California, Irvine, study conducted on mice with Alzheimer's that were given niacinamide showed cognitive deficits restored by the supplement. To date, no study has shown that niacinamide supplementation in humans helps Alzheimer's disease, although there currently is a study in the works at UC Irvine," reports naturopathic doctor Mark Stengler, in the July, 2011 issue of his newsletter, Bottom Line Natural Healing. To learn more about Dr. Stengler, go to www.DrStengler.com.
Bottom Line Natural Healing with Dr. Mark Stengler, July 2011, by Mark Stengler, NMD
Alternatives newsletter, February 2009, by Dr. David Williams.
J Neurosci 08:28:11500-11510
Nutrition & Healing newsletter, March 2009, by Jonathan Wright, M.D.
Life Extension magazine, April 2009, p. 22
Galantamine, Cocoa Flavonols for Alzheimer's
Alzheimer's patients given galantamine as an Alzheimers treatment showed less cognitive decline and lower mortality rates, reported investigators at an annual meeting of Neuropsychopharmacology. In fact, this Alzheimers treatment study was terminated early, due to the signficant differences in those participants taking galantamine vs. those given a placebo. In the brain, galantamine slows the breakdown of acetylcholine, a neurotransmitter necessary for learning and memory. To prevent stomach upset, start with a low dose (8 mg a day) says Julian Whitaker, M.D., and work gradually up to 24 mg daily, if needed.
Cocoa flavanols have also been shown to slow age-related loss of cognitive function.
Source: Health and Healing newsletter, by Julian Whitaker, M.D. March 2013
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